Debat dengam Prof.Vicente F.Corrales-Medina,MD, author of DHF IN Lange, Current Medical Diagnosis & Treatment 2009

From: taufiq mw [mailto:taufiqmw@yahoo.com]
Sent: Sun 2/15/2009 12:02 AM
To: Shandera, Wayne X; Corrales Medina, Vicente Francisco
Subject: New Debate About DHF

I'm buying your book: Lange, Current Medical Diagnosis and Treatment 2009
and I read about Dengue Haemorragic Fever.
I'm very dissapointed about that....
Please click: http://www.dhf-revolution.blogspot.com
I said the pathophisiology and pathogenesis of Dengue Haemorragic Fever is hypersensitive Type III (my research)
C'mon discuss with me...
Leave a comments about that site...
or you can just answer from my email....



From: "Corrales Medina, Vicente Francisco"
To: taufiq mw
Cc: "Shandera, Wayne X"
Sent: Tuesday, February 17, 2009 5:53:55 AM
Subject: RE: New Debate About DHF
Dear Dr. Waly:

Thank you for your communication and for trusting CMDT as your source for medical consultation. In regards to our section on DHF, we should emphasize that the goal of our review is to provide our readers with the most useful and updated CLINICAL information about this condition. Although we find both your hypothesis and approach very interesting, we prefer not to comment on pathophysiologic aspects of the disease that are still under investigation or do not have an established clinical application yet. Nevertheless, we will keep a close eye on the development or your line of research and we hope to see it published and discussed in peer review journals in the near future.


Best regards,


Vicente F. Corrales-Medina, M.D.


Dear dr. Medina:

I understands about your reason and I feel grateful because you already read about my research. It's interesting for me that we, as the intellectual to be patient with the basic of pathophysiology and pathogenesis dengue hemorrhagic fever which is not supported with a complete data and couldn't answer my critical question like what I've wrote in my blog. Our stubbornness by just giving fluid on DHF patient with serious thrombocytopenia without giving steroid, I consider it's a very brave action and I'm very sure if it will annoying our deepest heart, as the intelectual people. For the humanity good, every single thing that appear as the benefit for us wherever it exist, we must look for it. For instance: in internet, international journal, domestic journal, or even if it appear in the cave we must admire it, give the comment for it, or propose to take it if it is necessary.

May God always guide us ! Amen...

Diskusi dengan Prof. Paul R. Epstein, M.D., M.P.H Harvard Medical School

At 11:30 AM 2/4/2009, taufiq mw wrote:
> I have research about DHF (Dengue Haemorrhagic Fever), maybe interesting for you...
> I said about possibility new pathogenesis, new pathophysiology, and new treatment for DHF.
> Please see my blog at: Http://www.dhf-revolution.blogspot.com
> Thank you very much...
>
>
> Dr. Taufiq M Waly (Internist)



Thank you, Dr. Taufiq M Waly,

Are you now using steroids routinely for thrombocytopenia in DHF?

Paul


Paul R. Epstein, M.D., M.P.H.
Associate Director
Center for Health and the Global Environment
Harvard Medical School
Landmark Center
401 Park Drive, Second Floor
Boston, MA 02215

Tel. 617-384-8586
Fax. 617-384-8585
Email. paul_epstein@hms.harvard.edu
Website. http://chge. med.harvard.edu



Thank you for your question Mr. Paul.

Because I consider the basic of pathogenesis and pathophysiology in DHF is Hipersensitivity reaction type III that is proven by thrombocyte antibody (in my reserach) so, it has been a must for us to give the steroit to DHF patient. Steroit always be given to DHF patient with fever <5 days if the thrombocytes are <100.000/mm3 or if thrombocyte decreasing so fast in monitoring thrombocyte count. For example, in three times examination, count of thrombocyte decreased from 200.000 to 150.000 and then down to 120.000. For DHF patient with fever 5 days or more steroid should be given if thrombocyte shows a decreation trend in monitoring count of thrombocyte or if the thrombocyte decreasing faster (>50.000/mm3) in monitoring. It is the best if we give the steroit when thromboyte antibody has been proven as positive. Contra indication to give steroid if the patient have gastrointestinal bleeding.


What do you think about that Mr. Paul ?